Preparation of multiblock copolymers via step-wise addition of l-lactide and trimethylene carbonate
نویسندگان
چکیده
منابع مشابه
Synthesis and Characterization of a Novel Terpolymer Based on L-lactide, D,L-lactide and Trimethylene Carbonate
Terpolymers of L-lactide, D,L-lactide and trimethylene carbonate (TMC) were synthesized via the ring-opening polymerization reaction for cyclic monomers using stannous octoate as the initiator at a ratio of ~0.05 mol% (monomers/(SnOct) 2 ). Synthesis was done at 130 °C for 48 h. The inclusion of TMC, an aliphatic elastomeric polycarbonate, alongside polymer chain segments containing L-lactide a...
متن کاملEffect of the Configuration of a Bulky Aluminum Initiator on the Structure of Copolymers of L,L-Lactide with Symmetric Comonomer Trimethylene Carbonate
The effect of configuration of an asymmetric bulky initiator 2,2′-[1,1′-binaphtyl-2,2′-diylbis-(nitrylomethilidyne)]diphenoxy aluminum isopropoxide (Ini) on structure of copolymer of asymmetric monomer L,L-lactide (Lac) with symmetric comonomer trimethylene carbonate (Tmc) was studied using polarimetry, dilatometry, Size Exclusion Chromatography (SEC), and Carbon Nuclear Magnetic Resonance (13C...
متن کاملSynthesis, Characterization, and Osteoblastic Cell Culture of Poly(L-co-D,L-lactide-co-trimethylene carbonate) Scaffolds
Lactide-based polymers have been widely investigated as materials for tissue engineering. However, characteristics such as low flexibility and elongation tend to limit particular applications, although these can be enhanced by adding plasticizers such as trimethylene carbonate (TMC) to the polymer chain of the copolymer poly(L-lactide-co-D,L-lactide) (PLDLA). The aim of this work was to synthes...
متن کاملPoly(lactide-co-trimethylene carbonate) and Polylactide/Polytrimethylene Carbonate Blown Films
In this work, poly(lactide-co-trimethylene carbonate) and polylactide/ polytrimethylene carbonate films are prepared using a film blowing method. The process parameters, including temperature and screw speed, are studied, and the structures and properties of the P(LA-TMC) and PLA/PTMC films are investigated. The scanning electron microscope (SEM) images show that upon improving the content of T...
متن کاملComparison of accelerated and real-time cyclosporine A release testing from poly(l-lactide-co-trimethylene carbonate) matrices.
Cyclosporine A (CyA) is a cyclic undecapeptide, used in prophylaxis and therapy of graft rejection in all types of solid organ and bone narrow transplantations, as well as in treatment of a number of autoimmune diseases. However, prolonged repeated treatment with CyA may cause many side effects like nephrotoxicity, gingival hyperplasia and neurological disorders (1). Several controlled delivery...
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ژورنال
عنوان ژورنال: Chemical Science
سال: 2018
ISSN: 2041-6520,2041-6539
DOI: 10.1039/c7sc04507g